Sean O'Brien

Chaperone Therapeutics, Inc. develops disease-modifying therapies for neurodegenerative and rare diseases caused by protein misfolding. Its therapeutic approach elevates the natural protein folding and stress protection mechanisms to prevent protein misfolding and the ensuing cell dysfunction and death. The company is headquartered in Chapel Hill, NC

Riparian Pharmaceuticals, Inc. engages in the provision of vascular health therapeutic services. It also provides therapeutics to reverse endothelial dysfunction. The company was founded by Will Adams and Guillermo Garcia-Cardena and is headquartered in Watertown, MA.

Mebias Discovery, LLC engages in discovering drugs. The company was founded by Lawrence C. Kuo, Brett A. Tounge and Shariff S. Bayoumy in January 2016 and is headquartered in Philadelphia, PA.