Dennis Langer

Sirna Therapeutics, Inc. creates potent and stable siRNA compounds that are delivered into human cells resulting in the silencing of genes and viruses responsible for human diseases. The firm creates RNAi- based therapies to treat patients. The company was founded in 1992 and is headquartered in San Francisco, CA.

Transkaryotic Therapies, Inc. (TKT) was a biopharmaceutical company with a major focus on developing products for the treatment of rare diseases. The company is used to markets one product, Replagal™, for the treatment of Fabry disease in the European Union and other countries, and was developing products for Hunter syndrome and Gaucher disease. The company was located in Cambridge, MA.

Pharmacopeia LLC develops small molecule therapeutics to address significant medical needs. The firm operates as clinical development stage Biopharmaceutical Company which focuses on discovering and developing novel small molecule therapeutics to address medical needs. The company was founded by John J. Baldwin in February 2002 and is headquartered in Cranbury, NJ.

Inotek Pharmaceuticals Corp. is a clinical-stage biopharmaceutical company. It focuses on the discovery, development and commercialization of therapies for glaucoma and other diseases of the eye. The company's product candidate includes Trabodenoson, an adenosine mimetic that has completed Phase II clinical trials for lowering IOP by restoring the eye's natural pressure control mechanism. It is also developing Trabodenoson plus Latanoprost, a prostaglandin analogue that has completed Phase II clinical trials for use in patients with inadequate responses to treatment with latanoprost; and Trabodenoson monotherapy for the treatment of optic nerve neuropathy. Inotek Pharmaceuticals was founded on July 7, 1999 by Csaba Szabo and Andrew L. Salzman and is headquartered in Lexington, MA.

Auxilium Pharmaceuticals LLC develops and markets pharmaceutical products. It specializes in men's healthcare area and has product portfolio and pipeline in orthopedics, dermatology and other therapeutic areas. The firm products include edex, Osbon, ErecAid, STENDRA, TESTOPEL, XIAFLEX and Testim. The company was founded by Gerri A. Henwood and Jane Holmes Hollingsworth in 1999 and is headquartered in Chesterbrook, PA.

enGene, Inc. develops therapeutic solutions for the treatment of metabolic diseases. It operates as a biotechnology company which develops a mucosal immunotherapy platform for treating several prevalent, chronic diseases including inflammatory bowel disease and diabetes. The firm also develops proprietary, non-integrating biopolymer based nucleotide DNA and siRNA delivery technology that facilitates localized delivery of immune-modulating proteins to the intestinal mucosa for treating various immune disorders. The company was founded in 1999 by Anthony T. Cheung, John C. Brown, Timothy J. Kieffer, and Francis John Gargiulo and is headquartered in Vancouver, Canada.

Light Sciences Oncology, Inc. operates as a pharmaceutical company. It develops Aptocine for the treatment of solid tumors as well as other indications such as benign prostatic hyperplasia. The company was founded in 1994 and is headquartered in Bellevue, WA.

Ception Therapeutics, Inc. Develops pharmaceutical products. It focuses on the discovery and development of novel products to address areas of unmet medical need. The company was founded in 2004 and is headquartered in Malvern, PA.

Dicerna Pharmaceuticals, Inc. is a biopharmaceutical company, which engages in discovering, developing and commercializing medicines that are designed to leverage ribonucleic acid interference (RNAi) to selectively silence genes that cause or contribute to disease. The firm uses its proprietary GalXC RNAi technology platform to build a pipeline in these therapeutic areas. The company was founded by Douglas M. Fambrough III, Mark A. Behlke, Roberto Guerciolini, James Craig Jenson, and John J. Rossi in October 2006 and is headquartered in Lexington, MA.

Alzheon, Inc. engages in the provision of medical development. It specializes in treatment for brain health, memory, and aging. It offers ALZ-801, an oral small molecule inhibitor of amyloid formation and neurotoxicity with potential to be a therapy for a genetically defined population of patients with or at high risk for Alzheimer's disease and other neurodegenerative disorders. The company was founded by Martin Tolar in June 2013 and is headquartered in Framingham, MA.

Whitehead Institute for Biomedical Research provides research and technology services. Its services include biomedical, genomics, and genetics for students. The company was founded by Edwin C. Whitehead in 1982 and is headquartered in Cambridge, MA.

Shire Human Genetic Therapies, Inc. develops medicines for the treatment of genetic diseases. The company was founded on July 7, 1988 and is headquartered in Lexington, MA.

Phoenix IP Ventures LLC (PIPV Capital) is a private equity and venture capital firm founded in 2004 by Osagie Imasogie, Linda Gray and Zoltan Kerekes. The firm is headquartered in Philadelphia, Pennsylvania.

AdvanDx, Inc. provides advanced molecular diagnostic products for the prevention, diagnosis and treatment of life-threatening, bacterial infections. Its products include QuickFISH BC Tests, PNA FISH Tests, ASR PNA Probes, starter system, accessories and package inserts. The firm offers diagnostic solutions that include antimicrobial stewardship, blood culture contamination, staphylococcal bacteremia, enterococcal bacteremia, gram-negative bacteremia and candidemia. The company was founded by Henrik Stender and Thais T. Johansen in 2002 and is headquartered in Woburn, MA.

Dr. Reddy's Laboratories, Inc. develops pharmaceutical products. It also provides research and development activities and other medical testing services. The company is headquartered in Charlotte, NC.

Sancilio & Co., Inc. operates as specialty pharmaceutical company. It develops and markets based products including those based on the proprietary Advanced Lipid Technologies platform. The company was founded by Frederick D. Sancilio in 2005 and is headquartered in Riviera Beach, FL.

Searle & Co., Inc. provides investment advisory services. The business continuity plan addresses data back up and recovery, all mission critical systems, financial and operational assessments, alternative communications with customers, employees, regulators, alternate physical location of employees, critical supplier, contractor, bank and counter-party impact, regulatory reporting and assuring their customers prompt access to their funds and securities if they are unable to continue their business. The company was founded in 1982 and is headquartered in Greenwich, CT

GlaxoSmithKline LLC engages in discovering, developing, and delivering medicines, vaccines, and other healthcare products. It offers prescription medicines that treat various diseases, including cancer, HIV/AIDS, depression, diabetes, high blood pressure, herpes, asthma, migraine, and heart diseases, as well as stomach and skin problems, infections, and flu. It also provides vaccines for children and adults; and over-the-counter products. The company was founded in 1929 and is headquartered in Philadelphia, PA.

Smithkline Beecham Ltd. manufacture of basic pharmaceutical products. It also provides mineral water, bottled water, and soft drinks. The company was founded on January 24, 1989 and is headquartered in Brentford, the United Kingdom.

Pernix Therapeutics Holdings, Inc. engages in the research, development, and manufacture of biopharmaceutical products. It focuses on therapeutics for diseases on central nervous system, neurology, pain, and psychiatry. Its products include treatment of migraine pain and inflammation, insomnia, and depressive disorder. It distributes products through the following brands: Treximet, Silenor, and Zohydro ER with BeadTek. The company was founded in 1996 and is headquartered in Morristown, NJ.

Innocoll, Inc. developed and manufactured pharmaceutical products and medical devices. The company was headquartered in Ashburn, VA.

Sancilio Pharmaceuticals Co. engaged in the development and manufacture of pharmaceutical products. Its product platform, advanced lipid technologies, focuses on the treatment of diseases and disorders related to lipids such as sickle cell, short bowel, severe hypertriglyceridemia and non-alcoholic fatty liver. The company was founded by Frederick Sancilio in October 2004 and was headquartered in Riviera Beach, FL.

Braeburn, Inc. manufactures pharmaceutical products. It focuses on novel, long-acting implantable and injectable therapies for serious neurological and psychiatric disorders, including addiction, pain and schizophrenia. The firm develops Probuphine for the treatment of adult patients with opioid dependence. The company was founded in 2012 and is headquartered in Princeton, NJ.

Quoin Pharmaceuticals, Inc. manufactures pharmaceutical products. The company is headquartered in Las Vegas, NV.

Part of Ariceum Therapeutics GmbH, Theragnostics Ltd. is a British company that develops and distributes diagnostic devices and therapeutics. The private company is based in London, UK. The company was founded in 2013. Theragnostics was acquired by Ariceum Therapeutics GmbH on June 01, 2023 for $54.53 million.

Javelin Oncology, Inc. provides health care services. The company was founded by Anthony Cooper and is headquartered in Lebanon, NH.