M. Pauliina Margolis

Part of Medtronic Plc, InStent, Inc. is a company that develops self-expanding stents to open passageways in the body. The company is based in Eden Prairie, MN. The company was founded by Warren L. Bielke, Lewis C. Pell. InStent was acquired by Medtronic, Inc., part of Medtronic Plc from January 27, 2015 on June 28, 1996 for $214.60 million.

Heartport, Inc. develops systems and procedures for heart surgery. The company's technologies allow surgeons to perform a wide range of less invasive open-chest and minimally invasive heart operations, including stopped heart and beating heart procedures. Heartport was founded in 1991 and is headquartered in Redwood City, CA.

Direct Flow Medical, Inc. develops transcatheter heart valve technologies. It explores application of its technology beyond the aortic valve, to the mitral valve, and other valve anatomy. The firm’s Transcatheter Aortic Valve System is indicated for the treatment of patients with severe aortic stenosis, who are at risk for surgical aortic valve replacement. The company's system incorporates a polymer frame, which is expanded using pressurized saline and contrast for placement, assessment and repositioning. Direct Flow Medical was founded by Gordon B. Bishop and Randall T. Lashinski in June 2004 and is headquartered in Santa Rosa, CA.

TruTag Technologies, Inc. engages in the provision of precision-fabricated nano-porous silica for various applications and security solutions. It caters pharmaceutical and nutraceutical companies; secure labels and documents; and precision drug delivery systems for biotech companies. The company was founded by Hank C. K. Wuh in 2011 and is headquartered in Emeryville, CA.

Evalve, Inc. designs, develops, manufactures and markets devices. It developed a proprietary system which enables percutaneous repair of cardiac valves. The firm's products reduces the risks, trauma, and costs associated with current open, arrested heart surgical options. The company was founded on June 9, 1999 and is headquartered in Menlo Park, CA.

Biosense Webster, Inc. develops technology solutions for diagnosing heart rhythm disorders. It provides deflectable tip catheter for treating arrhythmia disorder. The company was founded by Wilton W. Webster Jr. and Shlomo Ben-Haim in 1998 and is headquartered in South Diamond Bar, CA.

Stryker GI Ltd. develops, manufactures and markets advanced endoscopic solutions for gastroenterological applications. The company was formerly known as SightLine Technologies. Stryker GI Israel was founded by Giora Bernat in December 1994 and is located in Haifa, Israel.

OrbiMed Advisors Private Equity (OrbiMed Advisors Private Equity) is a private equity and venture capital subsidiary of Orbimed Advisors LLC founded in 1993 by Samuel D. Isaly. The firm is headquartered in New York and it has additional offices in San Francisco, Mumbai, Shanghai, Herzliya, Hong Kong and London.

Part of Japan Lifeline Co., Ltd., Cardiac Rhythm Management is a company that manufactures implantable devices to treat arrhythmias. The company is based in Sylmar, CA.

MediaBoost Ltd. develops and markets real time decision making software solutions for auction based online advertising. The firm combines technology, science, methodology and art. It facilitates the complete customer acquisition and retention funnel which includes research, media planning, media buying, creative advertising, user experience control, conversion and monetization. The company was founded in 2004 and is headquartered in San Jose, CA.

Gilon Business Insight Ltd. develops software for information management and provides enterprise business intelligence consulting services. The company was founded in 1994 and is headquartered in Rosh Haayin, Israel.

RDD Pharma Ltd. develops pharmacological treatments for diseases of the anorectal region. The company was founded by Nir Barak in 2008 and is headquartered in Ramat Hachayal, Israel.

Otic Pharma Ltd. develops and manufactures pharmaceutical products for ear indications. Its products include FoamOtic Externa, FoamOtic Sinus, Foam-O-Vet, and FoamOtic Media. The company was founded by Gad Riesenfeld, Rodrigo A. Yelin and Eran Eilat in March 2008 and is headquartered in Irvine, CA.

American Medical Systems, Inc. manufactures and distributes medical devices. The company is headquartered in Minnetonka, MN.

cCAM Biotherapeutics Ltd. is a preclinical-stage company engaging in the development of immunotherapies to treat cancer. The company was founded by Silvia Noiman and Gal Markel in 2010 and is headquartered in Hod Ha'Sharon, Israel.

Broncus Medical, Inc. develops and commercializes medical devices for the diagnosis and treatment of lung cancer. Its products include Archimedes, Archimedes Planner, LungPoint VBN System, LungPoint Planner, and FleXNeedle. The company was founded on May 7, 2001 and is headquartered in San Jose, CA.

HIL Applied Medical Ltd. develops cancer Proton Therapy systems. It applies a patented approach, combining nanotechnology, and high-intensity lasers for its solutions. The company was founded by Shmuel Eisenmann and Arie Zigler in 2010 and is headquartered in Jerusalem, Israel.

3DSignals Ltd. develops an acoustics-based predictive maintenance technology for preventing unexpected machine failure. It provides Human Machine Interface (HMI) for real-time condition monitoring of mission-critical machinery, which reduces human operator errors and prevents unplanned downtimes. The firm’s specialties include reliability centered maintenance, big data analytics, and acoustic signal analysis. The company was founded by Amnon Shenfeld, Ofer Affias, Amit Ashkenazi, and Yair Lavi in 2015 and is headquartered in Kefar Sava, Israel.

SafeHeal SAS develops anastomosis protection devices for improved patient recovery and reduced healthcare costs. The company is headquartered in Paris, France.

510 Kardiac Devices, Inc. engages in the provision of cardiovascular devices. The company was founded by Jaime Sarabia in 2015 and is headquartered in Mableton, GA.

ImmPACT Bio USA, Inc. operates as a cell therapy company. The firm develops potent and selective engineered T-cells for the treatment of solid tumors. The company is headquartered in Camarillo, CA.

HighRAD Ltd. provides intelligent computer assessment support solutions. The company is based in Tel Aviv, Israel. Yossi Srour has been the CEO of the Israeli company since 2019.

Teuza Management and Development 1991 Ltd (Teuza Management and Development) is a venture capital firm founded in 1992 by Avi Kerbs and Joseph H. Gross. The firm is headquartered in Haifa, Israel.

ValCare Medical, Inc. engages in the designing, developing and commercializing devices and accessories for minimally invasive treatment of heart valve diseases. The firm develops a unique transcatheter device, which will provide the capability to implant the mitral annuloplasty device interventionally without surgery. The company was founded by Samuel M. Shaolian in 2012 and is headquartered in Herzlyia Pituach, Israel.